ZiaDerm Research is currently enrolling participants for a midface filler clinical trial in the Miami, Aventura, Broward, and Fort Lauderdale areas. Qualified participants will receive all study-related care from an experienced clinical research team. The study is evaluating an investigational hyaluronic acid dermal filler for cheek augmentation and correction of age-related midface volume loss compared with Restylane® Lyft™.
To Qualify:
- Must be 22 years of age or older
- Have noticeable loss of volume or fullness in the cheeks/midface
- Be interested in treatment to restore cheek or midface volume
- Have approximately similar volume loss on both sides of the face
- Be willing to avoid other facial aesthetic treatments during the study
- Be willing to travel to our locations and complete the required study visits
- No insurance is needed
- All study-related care is provided at no cost
- Participants may qualify for compensation for their time
The study requires participants to have moderate to severe-enough midface volume loss corresponding to Grade 2 or Grade 3 on the study’s Midface Volume Deficit Scale. This will be evaluated by the study team during screening.
To learn more, fill out the form on this page or call (786) 589-5183.
NO COST. NO INSURANCE. MAY QUALIFY FOR COMPENSATION.
Participants May Be Compensated for Their Time
- Study participation lasts approximately 65 to 83 weeks
- Participants receive an initial midface filler treatment
- An optional touch-up treatment may be given approximately 4 weeks after the initial treatment
- Participants may also be offered an optional retreatment approximately 65 weeks after their last initial/touch-up treatment
- Participants will attend a minimum of 9 on-site visits, with additional visits and follow-up calls depending on whether touch-up or retreatment is performed
The protocol describes individual participation lasting a minimum of 65 weeks and a maximum of approximately 83 weeks, or about 19 months.
What Is Midface Volume Loss?
Midface volume loss refers to a decrease in fullness in the cheeks and surrounding midface area. As people age, changes in facial fat and soft tissue can cause the cheeks to appear flatter, less full, or less defined.
Dermal fillers containing hyaluronic acid are commonly used to restore volume and improve cheek contour. This clinical trial is evaluating TPVM, an investigational hyaluronic acid dermal filler containing mepivacaine, compared with Restylane® Lyft™, an FDA-approved hyaluronic acid filler.
Participants are randomly assigned in a 3:1 ratio to receive either the investigational filler or Restylane Lyft. The treatment is injected into the cheek/midface area using a needle or cannula.
We are seeking adults who have lost noticeable fullness in their cheeks and would like treatment to improve midface volume. If this applies to you, you may qualify for the study.
About ZiaDerm Research
ZiaDerm Research is a clinical research center with more than 20 years of experience conducting dermatology clinical trials. Our experienced research staff and board-certified dermatologists have conducted hundreds of studies for companies including AbbVie, Eli Lilly, Galderma, and Pfizer.
ZiaDerm Research conducts Phase 2 through Phase 4 clinical trials, with participant safety as a top priority. To learn more about this midface filler clinical trial, the time commitment, participant responsibilities, and what to expect, fill out the form or call (786) 589-5183.